The University of Tennessee College of Medicine is committed to providing CME that is balanced, objective, and evidence based. In accordance with the Accreditation Council for Continuing Medical Education (ACCME) Essentials and Standards, all parties involved in content development are required to disclose any real or apparent conflicts of interest relating to the topics of this educational activity. The University of Tennessee College of Medicine has established mechanisms to resolve conflicts of interest should they arise. Any potential conflict of interest or off label use will be disclosed to the audience prior to the activity.